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(Repeat) Epigenetic editing – the power of CRISPR without DNA cutting


(Repeat) Epigenetic editing – the power of CRISPR without DNA cutting

Beyond Biotech – the podcast from Labiotech

(Repeat) Epigenetic editing – the power of CRISPR without DNA cutting

09.08.2024

Labiotech

While our podcast is taking a short break, Labiotech invites you to enjoy some of our favorite episodes. We will be back with a brand new episode on August 16, 2024! We hope you have a great summer!

Epic Bio is an epigenetic gene editing company that harnesses the power of CRISPR without cutting DNA.

The company’s proprietary Gene Expression Modulation System (GEMS) contains the smallest known Cas protein that functions in human cells and enables in vivo or ex vivo delivery via a single viral vector.

This week we discuss epigenetic editing, why it is reversible, and how it can be used to treat FSHD and other conditions with Dr. Stanley Qi, founder of Epic Bio and one of the original inventors of CRISPR.

01:15-02:51: Dr. Xi’s background
02:51-05:11: The beginning of Epic Bio
05:12–09:23: What is epigenetic editing?
09:23–10:47: What is the Gene Expression Modulation System?
10:47-12:47: How is the processing reversible?
12:47–18:01: How will epigenetic editing advance treatments?
18:01-21:24: Coping with multiple illnesses
21:24–22:46: How will your platform handle FSHD?
22:46-24:18: FSHD Clinical Study
24:18–25:51: How will you address costs?
25:51-27:18: Are other companies working on epigenetics?
27:18-29:27: What else is in the pipeline?
29:27–31:58: What are the next steps?

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